Mercedes-Benz CLS-Class MPG by Year & Engine (EPA)

EPA fuel-economy ratings for every rated Mercedes-Benz CLS-Class model year from 2006 to 2023 — each engine and transmission with its official city, highway and combined figures. Over these years the CLS-Class has been offered with 3.0L 6-cyl, 4.7L 8-cyl, 5.5L 8-cyl, 6.3L 8-cyl, 6.2L 8-cyl, 5.0L 8-cyl engines; the most efficient version is the 2021 (up to 26 MPG combined). Every rated gas version calls for premium gasoline. Data: U.S. Department of Energy & EPA, fueleconomy.gov; prices are live medians from VehiSales listings.

Mercedes-Benz CLS-Class fuel economy by year

YearCombinedEnginesMedian used priceFor sale
2023 25 MPG 3.0L 6-cyl $54,992 7 listings
2022 25 MPG 3.0L 6-cyl $44,900 11 listings
2021 25–26 MPG 3.0L 6-cyl $37,983 9 listings
2020 26 MPG 3.0L 6-cyl $38,000 14 listings
2019 26 MPG 3.0L 6-cyl $31,393 15 listings
2018 20–21 MPG 4.7L 8-cyl $25,398 5 listings
2017 20–21 MPG 4.7L 8-cyl $29,412 10 listings
2016 20–24 MPG 3.0L 6-cyl, 4.7L 8-cyl $20,495 15 listings
2015 18–24 MPG 3.0L 6-cyl, 4.7L 8-cyl, 5.5L 8-cyl $16,999 10 listings
2014 18–20 MPG 4.7L 8-cyl, 5.5L 8-cyl
2013 19–20 MPG 4.7L 8-cyl, 5.5L 8-cyl
2012 19–20 MPG 4.7L 8-cyl, 5.5L 8-cyl
2011 14–16 MPG 5.5L 8-cyl, 6.3L 8-cyl
2010 14–16 MPG 5.5L 8-cyl, 6.3L 8-cyl
2009 14–16 MPG 5.5L 8-cyl, 6.2L 8-cyl
2008 14–16 MPG 5.5L 8-cyl, 6.2L 8-cyl
2007 14–16 MPG 5.5L 8-cyl, 6.2L 8-cyl
2006 15–16 MPG 5.0L 8-cyl, 5.4L 8-cyl

2023 Mercedes-Benz CLS-Class: engines & MPG

The 2023 CLS-Class was EPA-rated in 1 version (3.0L 6-cyl), with combined economy of 25 MPG. Used 2023 models currently list for a median of $54,992 on VehiSales (7 for sale).

VersionEngineTransmissionFuelCityHwyCombined
CLS450 4matic 3.0L 6-cyl Automatic 9-spd Premium 22 30 25 MPG

2022 Mercedes-Benz CLS-Class: engines & MPG

The 2022 CLS-Class was EPA-rated in 1 version (3.0L 6-cyl), with combined economy of 25 MPG. Used 2022 models currently list for a median of $44,900 on VehiSales (11 for sale).

VersionEngineTransmissionFuelCityHwyCombined
CLS450 4matic 3.0L 6-cyl Automatic 9-spd Premium 22 30 25 MPG

2021 Mercedes-Benz CLS-Class: engines & MPG

The 2021 CLS-Class was EPA-rated in 2 versions (3.0L 6-cyl), with combined economy from 25 to 26 MPG. Used 2021 models currently list for a median of $37,983 on VehiSales (9 for sale).

VersionEngineTransmissionFuelCityHwyCombined
CLS450 3.0L 6-cyl Automatic 9-spd Premium 23 30 26 MPG
CLS450 4matic 3.0L 6-cyl Automatic 9-spd Premium 22 29 25 MPG

2020 Mercedes-Benz CLS-Class: engines & MPG

The 2020 CLS-Class was EPA-rated in 2 versions (3.0L 6-cyl), with combined economy of 26 MPG. Used 2020 models currently list for a median of $38,000 on VehiSales (14 for sale).

VersionEngineTransmissionFuelCityHwyCombined
CLS450 3.0L 6-cyl Automatic 9-spd Premium 24 31 26 MPG
CLS450 4matic 3.0L 6-cyl Automatic 9-spd Premium 23 30 26 MPG

2019 Mercedes-Benz CLS-Class: engines & MPG

The 2019 CLS-Class was EPA-rated in 2 versions (3.0L 6-cyl), with combined economy of 26 MPG. Used 2019 models currently list for a median of $31,393 on VehiSales (15 for sale).

VersionEngineTransmissionFuelCityHwyCombined
CLS450 4matic 3.0L 6-cyl Automatic 9-spd Premium 23 30 26 MPG
CLS450 3.0L 6-cyl Automatic 9-spd Premium 24 31 26 MPG

2018 Mercedes-Benz CLS-Class: engines & MPG

The 2018 CLS-Class was EPA-rated in 2 versions (4.7L 8-cyl), with combined economy from 20 to 21 MPG. Used 2018 models currently list for a median of $25,398 on VehiSales (5 for sale).

VersionEngineTransmissionFuelCityHwyCombined
CLS550 4.7L 8-cyl Automatic 9-spd Premium 18 26 21 MPG
CLS550 4matic 4.7L 8-cyl Automatic 9-spd Premium 17 25 20 MPG

2017 Mercedes-Benz CLS-Class: engines & MPG

The 2017 CLS-Class was EPA-rated in 2 versions (4.7L 8-cyl), with combined economy from 20 to 21 MPG. Used 2017 models currently list for a median of $29,412 on VehiSales (10 for sale).

VersionEngineTransmissionFuelCityHwyCombined
CLS550 4.7L 8-cyl Automatic 9-spd Premium 18 26 21 MPG
CLS550 4matic 4.7L 8-cyl Automatic 9-spd Premium 17 25 20 MPG

2016 Mercedes-Benz CLS-Class: engines & MPG

The 2016 CLS-Class was EPA-rated in 4 versions (3.0L 6-cyl, 4.7L 8-cyl), with combined economy from 20 to 24 MPG. Used 2016 models currently list for a median of $20,495 on VehiSales (15 for sale).

VersionEngineTransmissionFuelCityHwyCombined
CLS400 3.0L 6-cyl Automatic 7-spd Premium 20 30 24 MPG
CLS400 4matic 3.0L 6-cyl Automatic 7-spd Premium 19 26 22 MPG
CLS550 4matic 4.7L 8-cyl Automatic 9-spd Premium 17 25 20 MPG
CLS550 4.7L 8-cyl Automatic 9-spd Premium 18 26 20 MPG

2015 Mercedes-Benz CLS-Class: engines & MPG

The 2015 CLS-Class was EPA-rated in 5 versions (3.0L 6-cyl, 4.7L 8-cyl, 5.5L 8-cyl), with combined economy from 18 to 24 MPG. Used 2015 models currently list for a median of $16,999 on VehiSales (10 for sale).

VersionEngineTransmissionFuelCityHwyCombined
CLS400 3.0L 6-cyl Automatic 7-spd Premium 20 29 24 MPG
CLS400 4matic 3.0L 6-cyl Automatic 7-spd Premium 19 26 22 MPG
CLS550 4.7L 8-cyl Automatic 9-spd Premium 18 26 20 MPG
CLS550 4matic 4.7L 8-cyl Automatic 7-spd Premium 17 24 19 MPG
CLS63 AMG S 4matic 5.5L 8-cyl Automatic 7-spd Premium 16 22 18 MPG

2014 Mercedes-Benz CLS-Class: engines & MPG

The 2014 CLS-Class was EPA-rated in 6 versions (4.7L 8-cyl, 5.5L 8-cyl), with combined economy from 18 to 20 MPG.

VersionEngineTransmissionFuelCityHwyCombined
CLS550 4.7L 8-cyl Automatic 7-spd Premium 17 25 20 MPG
CLS63 AMG 5.5L 8-cyl Automatic 7-spd Premium 16 25 19 MPG
CLS550 4matic 4.7L 8-cyl Automatic 7-spd Premium 17 24 19 MPG
CLS63 AMG S 5.5L 8-cyl Automatic 7-spd Premium 16 25 19 MPG
CLS63 AMG S 4matic 5.5L 8-cyl Automatic 7-spd Premium 16 22 18 MPG
CLS63 AMG 4matic 5.5L 8-cyl Automatic 7-spd Premium 16 22 18 MPG

2013 Mercedes-Benz CLS-Class: engines & MPG

The 2013 CLS-Class was EPA-rated in 3 versions (4.7L 8-cyl, 5.5L 8-cyl), with combined economy from 19 to 20 MPG.

VersionEngineTransmissionFuelCityHwyCombined
CLS550 4.7L 8-cyl Automatic 7-spd Premium 17 25 20 MPG
CLS63 AMG 5.5L 8-cyl Automatic 7-spd Premium 16 25 19 MPG
CLS550 4matic 4.7L 8-cyl Automatic 7-spd Premium 16 25 19 MPG

2012 Mercedes-Benz CLS-Class: engines & MPG

The 2012 CLS-Class was EPA-rated in 3 versions (4.7L 8-cyl, 5.5L 8-cyl), with combined economy from 19 to 20 MPG.

VersionEngineTransmissionFuelCityHwyCombined
CLS550 4.7L 8-cyl Automatic 7-spd Premium 17 25 20 MPG
CLS63 AMG 5.5L 8-cyl Automatic 7-spd Premium 16 25 19 MPG
CLS550 4matic 4.7L 8-cyl Automatic 7-spd Premium 16 25 19 MPG

2011 Mercedes-Benz CLS-Class: engines & MPG

The 2011 CLS-Class was EPA-rated in 2 versions (5.5L 8-cyl, 6.3L 8-cyl), with combined economy from 14 to 16 MPG.

VersionEngineTransmissionFuelCityHwyCombined
CLS550 5.5L 8-cyl Automatic 7-spd Premium 14 21 16 MPG
CLS63 AMG 6.3L 8-cyl Automatic 7-spd Premium 12 18 14 MPG

2010 Mercedes-Benz CLS-Class: engines & MPG

The 2010 CLS-Class was EPA-rated in 2 versions (5.5L 8-cyl, 6.3L 8-cyl), with combined economy from 14 to 16 MPG.

VersionEngineTransmissionFuelCityHwyCombined
CLS550 5.5L 8-cyl Automatic 7-spd Premium 14 21 16 MPG
CLS63 AMG 6.3L 8-cyl Automatic 7-spd Premium 12 18 14 MPG

2009 Mercedes-Benz CLS-Class: engines & MPG

The 2009 CLS-Class was EPA-rated in 2 versions (5.5L 8-cyl, 6.2L 8-cyl), with combined economy from 14 to 16 MPG.

VersionEngineTransmissionFuelCityHwyCombined
CLS550 5.5L 8-cyl Automatic 7-spd Premium 14 21 16 MPG
CLS63 AMG 6.2L 8-cyl Automatic (S7) Premium 12 18 14 MPG

2008 Mercedes-Benz CLS-Class: engines & MPG

The 2008 CLS-Class was EPA-rated in 2 versions (5.5L 8-cyl, 6.2L 8-cyl), with combined economy from 14 to 16 MPG.

VersionEngineTransmissionFuelCityHwyCombined
CLS550 5.5L 8-cyl Automatic 7-spd Premium 14 21 16 MPG
CLS63 AMG 6.2L 8-cyl Automatic (S7) Premium 12 18 14 MPG

2007 Mercedes-Benz CLS-Class: engines & MPG

The 2007 CLS-Class was EPA-rated in 2 versions (5.5L 8-cyl, 6.2L 8-cyl), with combined economy from 14 to 16 MPG.

VersionEngineTransmissionFuelCityHwyCombined
CLS550 5.5L 8-cyl Automatic 7-spd Premium 14 20 16 MPG
CLS63 AMG 6.2L 8-cyl Automatic (S7) Premium 12 18 14 MPG

2006 Mercedes-Benz CLS-Class: engines & MPG

The 2006 CLS-Class was EPA-rated in 2 versions (5.0L 8-cyl, 5.4L 8-cyl), with combined economy from 15 to 16 MPG.

VersionEngineTransmissionFuelCityHwyCombined
CLS500 5.0L 8-cyl Automatic 7-spd Premium 14 20 16 MPG
CLS55 AMG 5.4L 8-cyl Automatic (S5) Premium 13 19 15 MPG

Frequently asked questions

What MPG does a Mercedes-Benz CLS-Class get?

Depending on year and engine, EPA combined ratings for the CLS-Class range from 16 to 26 MPG. The most efficient rated version is the 2021 model year.

What engines does the 2023 Mercedes-Benz CLS-Class have?

The 2023 CLS-Class was EPA-rated with 3.0L 6-cyl engines — see the 2023 table above for each version's exact city/highway figures.

Does the Mercedes-Benz CLS-Class require premium gas?

Yes — every EPA-rated gas CLS-Class version specifies premium gasoline.

Is there a hybrid or electric CLS-Class?

Yes — the ratings above include hybrid versions; look for them in the per-year tables.

About this data: EPA ratings from the official U.S. DOE/EPA dataset (fueleconomy.gov), as of July 2026; refreshed monthly. Market prices and listing counts are live medians from VehiSales inventory, updated daily. How to cite: “VehiSales Research, Mercedes-Benz CLS-Class EPA Fuel Economy by Model Year” with a link to https://vehisales.com/research/fuel-economy/mercedes-benz/cls-class.

See also: Mercedes-Benz CLS-Class hub — live listings, prices & reliability · Used Mercedes-Benz CLS-Class prices by year · Most fuel-efficient cars by segment · Model price trends. Media inquiries: [email protected].

© 2026 VehiSales · Data from live US vehicle listings · Methodology · Editorial policy · About · Press: cite as “VehiSales Used Car Price Index” with a link to this page.