Lexus Rx 350 MPG by Year & Engine (EPA)
EPA fuel-economy ratings for every rated Lexus Rx 350 model year from 2007 to 2026 — each engine and transmission with its official city, highway and combined figures. Over these years the Rx 350 has been offered with 2.5L 4-cyl, 2.4L 4-cyl, 3.5L 6-cyl power plants; the most efficient version is the 2026 (up to 36 MPG combined). Data: U.S. Department of Energy & EPA, fueleconomy.gov; prices are live medians from VehiSales listings.
Lexus Rx 350 fuel economy by year
| Year | Combined MPG | Engines | Median used price | For sale |
|---|---|---|---|---|
| 2026 | 24–36 | 2.5L 4-cyl, 2.4L 4-cyl | $60,304 | 345 listings |
| 2025 | 24–36 | 2.5L 4-cyl, 2.4L 4-cyl | $52,991 | 14 listings |
| 2024 | 24–36 | 2.5L 4-cyl, 2.4L 4-cyl | $49,902 | 61 listings |
| 2023 | 24–36 | 2.5L 4-cyl, 2.4L 4-cyl | $47,952 | 198 listings |
| 2022 | 21–23 | 3.5L 6-cyl | $41,485 | 119 listings |
| 2021 | 21–23 | 3.5L 6-cyl | $35,998 | 136 listings |
| 2020 | 21–23 | 3.5L 6-cyl | $32,995 | 105 listings |
| 2019 | 21–23 | 3.5L 6-cyl | $29,425 | 77 listings |
| 2018 | 21–23 | 3.5L 6-cyl | $26,495 | 86 listings |
| 2017 | 22–23 | 3.5L 6-cyl | $23,393 | 299 listings |
| 2016 | 22–23 | 3.5L 6-cyl | $21,998 | 97 listings |
| 2015 | 20–21 | 3.5L 6-cyl | $17,552 | 210 listings |
| 2014 | 20–21 | 3.5L 6-cyl | — | — |
| 2013 | 20–21 | 3.5L 6-cyl | — | — |
| 2012 | 20–21 | 3.5L 6-cyl | — | — |
| 2011 | 20–21 | 3.5L 6-cyl | — | — |
| 2010 | 20–21 | 3.5L 6-cyl | — | — |
| 2009 | 19–20 | 3.5L 6-cyl | — | — |
| 2008 | 19–20 | 3.5L 6-cyl | — | — |
| 2007 | 19–20 | 3.5L 6-cyl | — | — |
2026 Lexus Rx 350: engines & MPG
The 2026 Rx 350 was EPA-rated in 3 versions (2.5L 4-cyl, 2.4L 4-cyl), with combined economy from 24 to 36 MPG. Used 2026 models currently list for a median of $60,304 on VehiSales (345 for sale).
| Version | Engine | Transmission | Fuel | City | Hwy | Combined |
|---|---|---|---|---|---|---|
| RX 350h AWD | 2.5L 4-cyl | Automatic (AV-S6) | Premium | 37 | 34 | 36 MPG |
| RX 350 | 2.4L 4-cyl | Automatic (S8) | Premium | 22 | 29 | 25 MPG |
| RX 350 AWD | 2.4L 4-cyl | Automatic (S8) | Premium | 21 | 28 | 24 MPG |
2025 Lexus Rx 350: engines & MPG
The 2025 Rx 350 was EPA-rated in 3 versions (2.5L 4-cyl, 2.4L 4-cyl), with combined economy from 24 to 36 MPG. Used 2025 models currently list for a median of $52,991 on VehiSales (14 for sale).
| Version | Engine | Transmission | Fuel | City | Hwy | Combined |
|---|---|---|---|---|---|---|
| RX 350h AWD | 2.5L 4-cyl | Automatic (AV-S6) | Premium | 37 | 34 | 36 MPG |
| RX 350 | 2.4L 4-cyl | Automatic (S8) | Premium | 22 | 29 | 25 MPG |
| RX 350 AWD | 2.4L 4-cyl | Automatic (S8) | Premium | 21 | 28 | 24 MPG |
2024 Lexus Rx 350: engines & MPG
The 2024 Rx 350 was EPA-rated in 3 versions (2.5L 4-cyl, 2.4L 4-cyl), with combined economy from 24 to 36 MPG. Used 2024 models currently list for a median of $49,902 on VehiSales (61 for sale).
| Version | Engine | Transmission | Fuel | City | Hwy | Combined |
|---|---|---|---|---|---|---|
| RX 350h AWD | 2.5L 4-cyl | Automatic (AV-S6) | Premium | 37 | 34 | 36 MPG |
| RX 350 | 2.4L 4-cyl | Automatic (S8) | Premium | 22 | 29 | 25 MPG |
| RX 350 AWD | 2.4L 4-cyl | Automatic (S8) | Premium | 21 | 28 | 24 MPG |
2023 Lexus Rx 350: engines & MPG
The 2023 Rx 350 was EPA-rated in 3 versions (2.5L 4-cyl, 2.4L 4-cyl), with combined economy from 24 to 36 MPG. Used 2023 models currently list for a median of $47,952 on VehiSales (198 for sale).
| Version | Engine | Transmission | Fuel | City | Hwy | Combined |
|---|---|---|---|---|---|---|
| RX 350h AWD | 2.5L 4-cyl | Automatic (AV-S6) | Premium | 37 | 34 | 36 MPG |
| RX 350 | 2.4L 4-cyl | Automatic (S8) | Premium | 22 | 29 | 25 MPG |
| RX 350 AWD | 2.4L 4-cyl | Automatic (S8) | Premium | 21 | 28 | 24 MPG |
2022 Lexus Rx 350: engines & MPG
The 2022 Rx 350 was EPA-rated in 4 versions (3.5L 6-cyl), with combined economy from 21 to 23 MPG. Used 2022 models currently list for a median of $41,485 on VehiSales (119 for sale).
| Version | Engine | Transmission | Fuel | City | Hwy | Combined |
|---|---|---|---|---|---|---|
| RX 350 | 3.5L 6-cyl | Automatic (S8) | Regular | 20 | 27 | 23 MPG |
| RX 350 L | 3.5L 6-cyl | Automatic (S8) | Regular | 19 | 26 | 22 MPG |
| RX 350 AWD | 3.5L 6-cyl | Automatic (S8) | Regular | 19 | 26 | 22 MPG |
| RX 350 L AWD | 3.5L 6-cyl | Automatic (S8) | Regular | 18 | 25 | 21 MPG |
2021 Lexus Rx 350: engines & MPG
The 2021 Rx 350 was EPA-rated in 4 versions (3.5L 6-cyl), with combined economy from 21 to 23 MPG. Used 2021 models currently list for a median of $35,998 on VehiSales (136 for sale).
| Version | Engine | Transmission | Fuel | City | Hwy | Combined |
|---|---|---|---|---|---|---|
| RX 350 | 3.5L 6-cyl | Automatic (S8) | Regular | 20 | 27 | 23 MPG |
| RX 350 L | 3.5L 6-cyl | Automatic (S8) | Regular | 19 | 26 | 22 MPG |
| RX 350 AWD | 3.5L 6-cyl | Automatic (S8) | Regular | 19 | 26 | 22 MPG |
| RX 350 L AWD | 3.5L 6-cyl | Automatic (S8) | Regular | 18 | 25 | 21 MPG |
2020 Lexus Rx 350: engines & MPG
The 2020 Rx 350 was EPA-rated in 4 versions (3.5L 6-cyl), with combined economy from 21 to 23 MPG. Used 2020 models currently list for a median of $32,995 on VehiSales (105 for sale).
| Version | Engine | Transmission | Fuel | City | Hwy | Combined |
|---|---|---|---|---|---|---|
| RX 350 | 3.5L 6-cyl | Automatic (S8) | Regular | 20 | 27 | 23 MPG |
| RX 350 L | 3.5L 6-cyl | Automatic (S8) | Regular | 19 | 26 | 22 MPG |
| RX 350 AWD | 3.5L 6-cyl | Automatic (S8) | Regular | 19 | 26 | 22 MPG |
| RX 350 L AWD | 3.5L 6-cyl | Automatic (S8) | Regular | 18 | 25 | 21 MPG |
2019 Lexus Rx 350: engines & MPG
The 2019 Rx 350 was EPA-rated in 4 versions (3.5L 6-cyl), with combined economy from 21 to 23 MPG. Used 2019 models currently list for a median of $29,425 on VehiSales (77 for sale).
| Version | Engine | Transmission | Fuel | City | Hwy | Combined |
|---|---|---|---|---|---|---|
| RX 350 | 3.5L 6-cyl | Automatic (S8) | Regular | 20 | 27 | 23 MPG |
| RX 350 L | 3.5L 6-cyl | Automatic (S8) | Regular | 19 | 26 | 22 MPG |
| RX 350 AWD | 3.5L 6-cyl | Automatic (S8) | Regular | 19 | 26 | 22 MPG |
| RX 350 L AWD | 3.5L 6-cyl | Automatic (S8) | Regular | 18 | 25 | 21 MPG |
2018 Lexus Rx 350: engines & MPG
The 2018 Rx 350 was EPA-rated in 4 versions (3.5L 6-cyl), with combined economy from 21 to 23 MPG. Used 2018 models currently list for a median of $26,495 on VehiSales (86 for sale).
| Version | Engine | Transmission | Fuel | City | Hwy | Combined |
|---|---|---|---|---|---|---|
| RX 350 | 3.5L 6-cyl | Automatic (S8) | Regular | 20 | 27 | 23 MPG |
| RX 350 L | 3.5L 6-cyl | Automatic (S8) | Regular | 19 | 26 | 22 MPG |
| RX 350 AWD | 3.5L 6-cyl | Automatic (S8) | Regular | 19 | 26 | 22 MPG |
| RX 350 L AWD | 3.5L 6-cyl | Automatic (S8) | Regular | 18 | 25 | 21 MPG |
2017 Lexus Rx 350: engines & MPG
The 2017 Rx 350 was EPA-rated in 2 versions (3.5L 6-cyl), with combined economy from 22 to 23 MPG. Used 2017 models currently list for a median of $23,393 on VehiSales (299 for sale).
| Version | Engine | Transmission | Fuel | City | Hwy | Combined |
|---|---|---|---|---|---|---|
| RX 350 | 3.5L 6-cyl | Automatic (S8) | Regular | 20 | 27 | 23 MPG |
| RX 350 AWD | 3.5L 6-cyl | Automatic (S8) | Regular | 19 | 26 | 22 MPG |
2016 Lexus Rx 350: engines & MPG
The 2016 Rx 350 was EPA-rated in 2 versions (3.5L 6-cyl), with combined economy from 22 to 23 MPG. Used 2016 models currently list for a median of $21,998 on VehiSales (97 for sale).
| Version | Engine | Transmission | Fuel | City | Hwy | Combined |
|---|---|---|---|---|---|---|
| RX 350 | 3.5L 6-cyl | Automatic (S8) | Regular | 20 | 27 | 23 MPG |
| RX 350 AWD | 3.5L 6-cyl | Automatic (S8) | Regular | 19 | 26 | 22 MPG |
2015 Lexus Rx 350: engines & MPG
The 2015 Rx 350 was EPA-rated in 3 versions (3.5L 6-cyl), with combined economy from 20 to 21 MPG. Used 2015 models currently list for a median of $17,552 on VehiSales (210 for sale).
| Version | Engine | Transmission | Fuel | City | Hwy | Combined |
|---|---|---|---|---|---|---|
| RX 350 AWD | 3.5L 6-cyl | Automatic (S8) | Regular | 18 | 26 | 21 MPG |
| RX 350 | 3.5L 6-cyl | Automatic (S6) | Regular | 18 | 25 | 21 MPG |
| RX 350 AWD | 3.5L 6-cyl | Automatic (S6) | Regular | 18 | 24 | 20 MPG |
2014 Lexus Rx 350: engines & MPG
The 2014 Rx 350 was EPA-rated in 3 versions (3.5L 6-cyl), with combined economy from 20 to 21 MPG.
| Version | Engine | Transmission | Fuel | City | Hwy | Combined |
|---|---|---|---|---|---|---|
| RX 350 AWD | 3.5L 6-cyl | Automatic (S8) | Regular | 18 | 26 | 21 MPG |
| RX 350 | 3.5L 6-cyl | Automatic (S6) | Regular | 18 | 25 | 21 MPG |
| RX 350 AWD | 3.5L 6-cyl | Automatic (S6) | Regular | 18 | 24 | 20 MPG |
2013 Lexus Rx 350: engines & MPG
The 2013 Rx 350 was EPA-rated in 3 versions (3.5L 6-cyl), with combined economy from 20 to 21 MPG.
| Version | Engine | Transmission | Fuel | City | Hwy | Combined |
|---|---|---|---|---|---|---|
| RX 350 AWD | 3.5L 6-cyl | Automatic (S8) | Regular | 18 | 26 | 21 MPG |
| RX 350 | 3.5L 6-cyl | Automatic (S6) | Regular | 18 | 25 | 21 MPG |
| RX 350 AWD | 3.5L 6-cyl | Automatic (S6) | Regular | 18 | 24 | 20 MPG |
2012 Lexus Rx 350: engines & MPG
The 2012 Rx 350 was EPA-rated in 2 versions (3.5L 6-cyl), with combined economy from 20 to 21 MPG.
| Version | Engine | Transmission | Fuel | City | Hwy | Combined |
|---|---|---|---|---|---|---|
| RX 350 | 3.5L 6-cyl | Automatic (S6) | Regular | 18 | 25 | 21 MPG |
| RX 350 AWD | 3.5L 6-cyl | Automatic (S6) | Regular | 18 | 24 | 20 MPG |
2011 Lexus Rx 350: engines & MPG
The 2011 Rx 350 was EPA-rated in 2 versions (3.5L 6-cyl), with combined economy from 20 to 21 MPG.
| Version | Engine | Transmission | Fuel | City | Hwy | Combined |
|---|---|---|---|---|---|---|
| RX 350 2WD | 3.5L 6-cyl | Automatic (S6) | Premium | 18 | 24 | 21 MPG |
| RX 350 AWD | 3.5L 6-cyl | Automatic (S6) | Premium | 18 | 24 | 20 MPG |
2010 Lexus Rx 350: engines & MPG
The 2010 Rx 350 was EPA-rated in 2 versions (3.5L 6-cyl), with combined economy from 20 to 21 MPG.
| Version | Engine | Transmission | Fuel | City | Hwy | Combined |
|---|---|---|---|---|---|---|
| RX 350 2WD | 3.5L 6-cyl | Automatic (S6) | Premium | 18 | 25 | 21 MPG |
| RX 350 AWD | 3.5L 6-cyl | Automatic (S6) | Premium | 18 | 24 | 20 MPG |
2009 Lexus Rx 350: engines & MPG
The 2009 Rx 350 was EPA-rated in 4 versions (3.5L 6-cyl), with combined economy from 19 to 20 MPG.
| Version | Engine | Transmission | Fuel | City | Hwy | Combined |
|---|---|---|---|---|---|---|
| RX 350 2WD | 3.5L 6-cyl | Automatic (S5) | Premium | 18 | 23 | 20 MPG |
| RX 350 2WD | 3.5L 6-cyl | Automatic 5-spd | Premium | 18 | 23 | 20 MPG |
| RX 350 4WD | 3.5L 6-cyl | Automatic (S5) | Premium | 17 | 22 | 19 MPG |
| RX 350 4WD | 3.5L 6-cyl | Automatic 5-spd | Premium | 17 | 22 | 19 MPG |
2008 Lexus Rx 350: engines & MPG
The 2008 Rx 350 was EPA-rated in 4 versions (3.5L 6-cyl), with combined economy from 19 to 20 MPG.
| Version | Engine | Transmission | Fuel | City | Hwy | Combined |
|---|---|---|---|---|---|---|
| RX 350 2WD | 3.5L 6-cyl | Automatic 5-spd | Premium | 18 | 23 | 20 MPG |
| RX 350 2WD | 3.5L 6-cyl | Automatic (S5) | Premium | 18 | 23 | 20 MPG |
| RX 350 4WD | 3.5L 6-cyl | Automatic 5-spd | Premium | 17 | 22 | 19 MPG |
| RX 350 4WD | 3.5L 6-cyl | Automatic (S5) | Premium | 17 | 22 | 19 MPG |
2007 Lexus Rx 350: engines & MPG
The 2007 Rx 350 was EPA-rated in 4 versions (3.5L 6-cyl), with combined economy from 19 to 20 MPG.
| Version | Engine | Transmission | Fuel | City | Hwy | Combined |
|---|---|---|---|---|---|---|
| RX 350 2WD | 3.5L 6-cyl | Automatic 5-spd | Premium | 18 | 23 | 20 MPG |
| RX 350 2WD | 3.5L 6-cyl | Automatic (S5) | Premium | 18 | 23 | 20 MPG |
| RX 350 4WD | 3.5L 6-cyl | Automatic (S5) | Premium | 17 | 22 | 19 MPG |
| RX 350 4WD | 3.5L 6-cyl | Automatic 5-spd | Premium | 17 | 22 | 19 MPG |
Frequently asked questions
What MPG does a Lexus Rx 350 get?
Depending on year and engine, EPA combined economy for the Rx 350 ranges from 19 to 36 MPG. The most efficient rated version is the 2026 model year.
What engines does the 2026 Lexus Rx 350 have?
The 2026 Rx 350 was EPA-rated with 2.5L 4-cyl, 2.4L 4-cyl — see the 2026 table above for each version's exact city/highway figures.
Does the Lexus Rx 350 require premium gas?
Some versions do: EPA lists premium and regular depending on year and engine — check your year's table above.
Is there a hybrid or electric Rx 350?
Yes — the ratings above include hybrid versions; look for them in the per-year tables.
https://vehisales.com/research/fuel-economy/lexus/rx-350.
Underlying ratings are public-domain EPA/DOE data from fueleconomy.gov.
See also: Lexus Rx 350 hub — live listings, prices & reliability · Most fuel-efficient cars by segment · Model price trends. Media inquiries: [email protected].